Ehrlich Tumor Induces TRPV1-Dependent Evoked and Non-Evoked Pain-like Behavior in Mice

We standardized a model by injecting Ehrlich tumor cells into the paw to evaluate cancer pain mechanisms and pharmacological treatments. Opioid treatment, but not cyclooxygenase inhibitor or tricyclic antidepressant treatments reduces Ehrlich tumor pain. To best use this model for drug screening it...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Mariana M. Bertozzi, Telma Saraiva-Santos, Tiago H. Zaninelli, Felipe A. Pinho-Ribeiro, Victor Fattori, Larissa Staurengo-Ferrari, Camila R. Ferraz, Talita P. Domiciano, Cassia Calixto-Campos, Sergio M. Borghi, Ana C. Zarpelon, Thiago M. Cunha, Rubia Casagrande, Waldiceu A. Verri
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2022-09-01
סדרה:	Brain Sciences
נושאים:	AMG9810 calcium imaging cancer pain dorsal root ganglia Ehrlich tumor mechanical hyperalgesia
גישה מקוונת:	https://www.mdpi.com/2076-3425/12/9/1247
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