Ehrlich Tumor Induces TRPV1-Dependent Evoked and Non-Evoked Pain-like Behavior in Mice

We standardized a model by injecting Ehrlich tumor cells into the paw to evaluate cancer pain mechanisms and pharmacological treatments. Opioid treatment, but not cyclooxygenase inhibitor or tricyclic antidepressant treatments reduces Ehrlich tumor pain. To best use this model for drug screening it...

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Principais autores:	Mariana M. Bertozzi, Telma Saraiva-Santos, Tiago H. Zaninelli, Felipe A. Pinho-Ribeiro, Victor Fattori, Larissa Staurengo-Ferrari, Camila R. Ferraz, Talita P. Domiciano, Cassia Calixto-Campos, Sergio M. Borghi, Ana C. Zarpelon, Thiago M. Cunha, Rubia Casagrande, Waldiceu A. Verri
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-09-01
Serija:	Brain Sciences
Teme:	AMG9810 calcium imaging cancer pain dorsal root ganglia Ehrlich tumor mechanical hyperalgesia
Online dostop:	https://www.mdpi.com/2076-3425/12/9/1247
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