Benefits of equilibrium between microbiota- and host-derived ligands of the aryl hydrocarbon receptor after stroke in aged male mice

Abstract Recent studies have highlighted the crucial role of microglia (MG) and their interactions with the gut microbiome in post-stroke neuroinflammation. The activation of immunoregulatory pathways, including the aryl hydrocarbon receptor (AHR) pathway, is influenced by a dynamic balance of ligan...

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Главные авторы:	Pedram Peesh, Maria P. Blasco-Conesa, Ahmad El Hamamy, Romeesa Khan, Gary U. Guzman, Parisa Honarpisheh, Eric C. Mohan, Grant W. Goodman, Justin N. Nguyen, Anik Banerjee, Bryce E. West, Kyung Ae Ko, Janelle M. Korf, Chunfeng Tan, Huihui Fan, Gabriela D. Colpo, Hilda Ahnstedt, Lucy Couture, Solji Roh, Julia K. Kofler, Jose F. Moruno-Manchon, Michael E. Maniskas, Jaroslaw Aronowski, Rodney M. Ritzel, Juneyoung Lee, Jun Li, Robert M. Bryan, Anjali Chauhan, Venugopal Reddy Venna, Louise D. McCullough, Bhanu Priya Ganesh
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2025-02-01
Серии:	Nature Communications
Online-ссылка:	https://doi.org/10.1038/s41467-025-57014-2
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