Benefits of equilibrium between microbiota- and host-derived ligands of the aryl hydrocarbon receptor after stroke in aged male mice

Abstract Recent studies have highlighted the crucial role of microglia (MG) and their interactions with the gut microbiome in post-stroke neuroinflammation. The activation of immunoregulatory pathways, including the aryl hydrocarbon receptor (AHR) pathway, is influenced by a dynamic balance of ligan...

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Principais autores:	Pedram Peesh, Maria P. Blasco-Conesa, Ahmad El Hamamy, Romeesa Khan, Gary U. Guzman, Parisa Honarpisheh, Eric C. Mohan, Grant W. Goodman, Justin N. Nguyen, Anik Banerjee, Bryce E. West, Kyung Ae Ko, Janelle M. Korf, Chunfeng Tan, Huihui Fan, Gabriela D. Colpo, Hilda Ahnstedt, Lucy Couture, Solji Roh, Julia K. Kofler, Jose F. Moruno-Manchon, Michael E. Maniskas, Jaroslaw Aronowski, Rodney M. Ritzel, Juneyoung Lee, Jun Li, Robert M. Bryan, Anjali Chauhan, Venugopal Reddy Venna, Louise D. McCullough, Bhanu Priya Ganesh
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2025-02-01
Series:	Nature Communications
Acceso en liña:	https://doi.org/10.1038/s41467-025-57014-2
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