Prognostic stratification of sepsis through DNA damage response based RiskScore system: insights from single-cell RNA-sequencing and transcriptomic profiling

BackgroundA novel risk scoring system, predicated on DNA damage response (DDR), was developed to enhance prognostic predictions and potentially inform the creation of more effective therapeutic protocols for sepsis.MethodsTo thoroughly delineate the expression profiles of DDR markers within the cont...

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Auteurs principaux:	Qingjiang Lin, Rongyao Zeng, Jinfeng Yang, Zebo Xu, Shaoxiong Jin, Guan Wei
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-02-01
Collection:	Frontiers in Immunology
Sujets:	single-cell RNA-sequencing DNA damage response sepsis prognostic model immune response
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1345321/full
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