Prognostic stratification of sepsis through DNA damage response based RiskScore system: insights from single-cell RNA-sequencing and transcriptomic profiling

BackgroundA novel risk scoring system, predicated on DNA damage response (DDR), was developed to enhance prognostic predictions and potentially inform the creation of more effective therapeutic protocols for sepsis.MethodsTo thoroughly delineate the expression profiles of DDR markers within the cont...

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Autors principals:	Qingjiang Lin, Rongyao Zeng, Jinfeng Yang, Zebo Xu, Shaoxiong Jin, Guan Wei
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-02-01
Col·lecció:	Frontiers in Immunology
Matèries:	single-cell RNA-sequencing DNA damage response sepsis prognostic model immune response
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1345321/full
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