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Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression.

Silencing of T cell activation and function is a highly efficient strategy of immunosuppression induced by pathogens. By promoting formation of membrane microdomains essential for clustering of receptors and signalling platforms in the plasma membrane, ceramides accumulating as a result of membrane...

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Autori principali: Evelyn Gassert, Elita Avota, Harry Harms, Georg Krohne, Erich Gulbins, Sibylle Schneider-Schaulies
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2009-10-01
Serie:PLoS Pathogens
Accesso online:http://europepmc.org/articles/PMC2757718?pdf=render
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