Intracellular Salmonella delivery of an exogenous immunization antigen refocuses CD8 T cells against cancer cells, eliminates pancreatic tumors and forms antitumor immunity

IntroductionImmunotherapies have shown great promise, but are not effective for all tumors types and are effective in less than 3% of patients with pancreatic ductal adenocarcinomas (PDAC). To make an immune treatment that is effective for more cancer patients and those with PDAC specifically, we ge...

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Detaylı Bibliyografya

Asıl Yazarlar:	Vishnu Raman, Lars M. Howell, Shoshana M. K. Bloom, Christopher L. Hall, Victoria E. Wetherby, Lisa M. Minter, Ashish A. Kulkarni, Neil S. Forbes
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2023-10-01
Seri Bilgileri:	Frontiers in Immunology
Konular:	bacterial therapy CD8 T cells intracellular antigen delivery refocus of vaccine immunity exogenous antigen recall antigen
Online Erişim:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1228532/full
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