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Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase

Sphingolipids (SLs) have been extensively investigated in biomedical research due to their role as bioactive molecules in cells. Here, we describe the effect of a SL analog, jaspine B (JB), a cyclic anhydrophytosphingosine found in marine sponges, on the gastric cancer cell line, HGC-27. JB induced...

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Autors principals: Francesca Cingolani, Fabio Simbari, Jose Luis Abad, Mireia Casasampere, Gemma Fabrias, Anthony H. Futerman, Josefina Casas
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017-08-01
Col·lecció:Journal of Lipid Research
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S0022227520337780
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