DNMT3A-mediated high expression of circ_0057504 promotes benzo[a]pyrene-induced DNA damage via the NONO-SFPQ complex in human bronchial epithelial cells

Benzo[a]pyrene (B[a]P) is a class I carcinogen and hazardous environmental pollutant with genetic toxicity. Understanding the molecular mechanisms underlying genetic deterioration and epigenetic alterations induced by environmental contaminants may contribute to the early detection and prevention of...

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Hlavní autoři:	Miaoyun Qiu, Nan Zhang, Shuwei Yao, Hanyu Zhou, Xintong Chen, Yangyang Jia, Han Zhang, Xin Li, Yiguo Jiang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-12-01
Edice:	Environment International
Témata:	B[a]P DNA damage circRNA NONO-SFPQ complex DNMT3A
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0160412022005542
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