DNMT3A-mediated high expression of circ_0057504 promotes benzo[a]pyrene-induced DNA damage via the NONO-SFPQ complex in human bronchial epithelial cells

Benzo[a]pyrene (B[a]P) is a class I carcinogen and hazardous environmental pollutant with genetic toxicity. Understanding the molecular mechanisms underlying genetic deterioration and epigenetic alterations induced by environmental contaminants may contribute to the early detection and prevention of...

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Hauptverfasser:	Miaoyun Qiu, Nan Zhang, Shuwei Yao, Hanyu Zhou, Xintong Chen, Yangyang Jia, Han Zhang, Xin Li, Yiguo Jiang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2022-12-01
Schriftenreihe:	Environment International
Schlagworte:	B[a]P DNA damage circRNA NONO-SFPQ complex DNMT3A
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0160412022005542
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