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Obatoclax, the pan-Bcl-2 inhibitor sensitizes hepatocellular carcinoma cells to promote the anti-tumor efficacy in combination with immune checkpoint blockade

Bcl-2 family proteins play critical roles in regulating lymphocyte development and maintain homeostasis, and have also been proved to be involved in various cancer types development. However, the role of Bcl-2 in hepatocellular carcinoma (HCC) development has not been clearly studied. Here, we repor...

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Detalhes bibliográficos
Principais autores: Jingye Li, Jinrong Xu, Zhibing Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-08-01
coleção:Translational Oncology
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S193652332100108X
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