ATNT: an enhanced system for expression of polycistronic secondary metabolite gene clusters in Aspergillus niger

Abstract Background Fungi are treasure chests for yet unexplored natural products. However, exploitation of their real potential remains difficult as a significant proportion of biosynthetic gene clusters appears silent under standard laboratory conditions. Therefore, elucidation of novel products r...

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Bibliografische Detailangaben

Hauptverfasser:	Elena Geib, Matthias Brock
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2017-12-01
Schriftenreihe:	Fungal Biology and Biotechnology
Schlagworte:	Asp-melanin P2A Polycistronic mRNA Tet-on system Doxycycline Terrein biosynthetic gene cluster
Online-Zugang:	http://link.springer.com/article/10.1186/s40694-017-0042-1
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