Aberrant sphingosine-1-phosphate receptor 1 expression on activated naive B cells associated with disease activity and lupus nephritis in systemic lupus erythematosus

Abstract Background Systemic lupus erythematosus (SLE) is characterized by the immune system producing autoantibodies that target the body’s own cells and tissues, leading to inflammation and tissue damage. Sphingosine-1-phosphate receptor 1 (S1PR1) plays a crucial role in regulating immune cell tra...

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Bibliografiske detaljer

Principais autores:	Pachara Tianpothong, Piyawan Kochayoo, Thanitta Suangtamai, Sasicha Suksapan, Pongsakorn Thawornpan, Chaniya Leepiyasakulchai, Pintip Ngamjanyaporn, Prapaporn Pisitkun, Patchanee Chootong
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2026-05-01
Serier:	Arthritis Research & Therapy
Fag:	Sphingosine-1-phosphate receptor 1 Activated naive B cells Systemic lupus erythematosus
Online adgang:	https://doi.org/10.1186/s13075-026-03829-3
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