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Recurrent genomic gains in preinvasive lesions as a biomarker of risk for lung cancer.

Lung carcinoma development is accompanied by field changes that may have diagnostic significance. We have previously shown the importance of chromosomal aneusomy in lung cancer progression. Here, we tested whether genomic gains in six specific loci, TP63 on 3q28, EGFR on 7p12, MYC on 8q24, 5p15.2, a...

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Main Authors: Pierre P Massion, Yong Zou, Hasmet Uner, Porntip Kiatsimkul, Holly J Wolf, Anna E Baron, Tim Byers, Steinn Jonsson, Stephen Lam, Fred R Hirsch, York E Miller, Wilbur A Franklin, Marileila Varella-Garcia
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2699220?pdf=render
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