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Protocol for in situ Proximity Ligation Assay (PLA) and Microscopy Analysis of Epidermal Growth Factor Receptor (EGFR) Homodimerization

Oncogenic drivers play central roles in tumorigenesis as well as in tumor cell survival and proliferation. Mutations of the epidermal growth factor receptor gene (EGFR) that result in constitutive activation of the receptor tyrosine kinase have been identified as oncogenic drivers in a subset of non...

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Autori principali: Keiichi Ota, Taishi Harada
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bio-protocol LLC 2018-11-01
Serie:Bio-Protocol
Accesso online:https://bio-protocol.org/en/bpdetail?id=3067&type=0
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