Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis

Abstract Map3k8 has been proposed as a useful target for the treatment of inflammatory diseases. We show here that during lipopolysaccharide-induced emergency granulopoiesis, Map3k8 deficiency strongly impairs the increase in circulating mature (Ly6GhighCD11b+) and immature (Ly6GlowCD11b+) neutrophi...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Ángela Sánchez, Carlos Relaño, Araceli Carrasco, Constanza Contreras-Jurado, Antonio Martín-Duce, Ana Aranda, Susana Alemany
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2017-07-01
Sarja:	Scientific Reports
Linkit:	https://doi.org/10.1038/s41598-017-04538-3
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