Epigenome-wide analysis identifies DNA methylation signatures associated with the infant pupillary light reflex, a candidate intermediate phenotype for autism

Abstract The pupillary light reflex (PLR), the automatic constriction of the pupil in response to increased luminance, is a candidate early intermediate phenotype associated with autism, with potential to help understand early neurodevelopmental differences because it is controlled by relatively sim...

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Manylion Llyfryddiaeth

Prif Awduron:	Laurel A. Fish, Teodora Gliga, Anna Gui, Jannath Begum Ali, Luke Mason, Mark H. Johnson, Tony Charman, Terje Falck-Ytter, Emily J. H. Jones, Radhika Kandaswamy, Francesca Happé, Chloe C. Y. Wong
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Nature Portfolio 2026-01-01
Cyfres:	Scientific Reports
Pynciau:	Pupillary light reflex (PLR) Epigenetics DNA methylation Autism Intermediate phenotype
Mynediad Ar-lein:	https://doi.org/10.1038/s41598-025-31651-5
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