A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway

Abstract Background Colorectal cancer (CRC) is a heterogeneous tumor having various genetic alterations. The current treatment options had limited impact on disease free survival due to therapeutic resistance. Novel anticancer agents are needed to treat CRC specifically metastatic colorectal cancer....

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Principais autores:	Khayal Al-Khayal, Mansoor-Ali Vaali-Mohammed, Mohammed Elwatidy, Thamer Bin Traiki, Omar Al-Obeed, Mohammad Azam, Zahid Khan, Maha Abdulla, Rehan Ahmad
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2020-07-01
סדרה:	BMC Cancer
נושאים:	Apoptosis Platinum Redox balance Colorectal Cancer MAPK
גישה מקוונת:	http://link.springer.com/article/10.1186/s12885-020-07165-w
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!