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Engineering circuits of human iPSC-derived neurons and rat primary glia

Novel in vitro platforms based on human neurons are needed to improve early drug testing and address the stalling drug discovery in neurological disorders. Topologically controlled circuits of human induced pluripotent stem cell (iPSC)-derived neurons have the potential to become such a testing syst...

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Furkejuvvon:
Váldodahkkit: Sophie Girardin, Stephan J. Ihle, Arianna Menghini, Magdalena Krubner, Leonardo Tognola, Jens Duru, Isabelle Fruh, Matthias Müller, Tobias Ruff, János Vörös
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2023-05-01
Ráidu:Frontiers in Neuroscience
Fáttát:
bottom-up neuroscience
iPSC-derived neurons
glial cells
in vitro neural circuit
microelectrode arrays
magnesium
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fnins.2023.1103437/full
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