Engineering circuits of human iPSC-derived neurons and rat primary glia

Novel in vitro platforms based on human neurons are needed to improve early drug testing and address the stalling drug discovery in neurological disorders. Topologically controlled circuits of human induced pluripotent stem cell (iPSC)-derived neurons have the potential to become such a testing syst...

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主要な著者:	Sophie Girardin, Stephan J. Ihle, Arianna Menghini, Magdalena Krubner, Leonardo Tognola, Jens Duru, Isabelle Fruh, Matthias Müller, Tobias Ruff, János Vörös
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2023-05-01
シリーズ:	Frontiers in Neuroscience
主題:	bottom-up neuroscience iPSC-derived neurons glial cells in vitro neural circuit microelectrode arrays magnesium
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fnins.2023.1103437/full
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