Penfluridol targets septin7 to suppress endometrial cancer by septin7-Orai/IP3R-Ca2+-PIK3CA pathway

Summary: Phenotypic screening of existing drugs is a good strategy to discover new drugs. Herein, 33 psychotherapeutic drugs in our drug library were screened by phenotypic screening and penfluridol (PFD) was found to exhibit excellent anti-endometrial cancer (EC) activity both in vitro and in vivo....

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Váldodahkkit:	Lingyi Song, Huiwen Wu, Xiao Sun, Xiaohu Liu, Xianwu Ling, Wei Ni, Lijuan Li, Beibei Liu, Jinlian Wei, Xiaokang Li, Jian Li, Yudong Wang, Fei Mao
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Elsevier 2025-01-01
Ráidu:	iScience
Fáttát:	Cell biology Functional aspects of cell biology Cancer
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S2589004224028670
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