Unveiling the Impact of Morphine on Tamoxifen Metabolism in Mice in vivo
Background: Tamoxifen is used to treat breast cancer and cancer recurrences. After administration, tamoxifen is converted into two more potent antitumor compounds, 4OH-tamoxifen and endoxifen by the CYP3A4/5 and 2D6 enzymes in human. These active compounds are inactivated by the same UDP-glucuronosy...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2020-02-01
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| Serija: | Frontiers in Oncology |
| Teme: | |
| Online dostop: | https://www.frontiersin.org/article/10.3389/fonc.2020.00025/full |
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