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Toll-like Receptor-Dependent Negative Effects of Opioids: A Battle between Analgesia and Hyperalgesia

Our understanding of the pathophysiology of the pathological pain and the pharmacology of analgesic treatments has progressed tremendously over the past two decades. Among the well-documented pro-algesic factors, glia and other toll-like receptors (TLRs)-expressing cells in the neuroimmune interface...

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Autori principali: Masaud Shah, Sangdun Choi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017-05-01
Serie:Frontiers in Immunology
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Accesso online:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00642/full
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