NTRK gene aberrations in triple‐negative breast cancer: detection challenges using IHC, FISH, RT‐PCR, and NGS

Abstract Triple‐negative breast cancer (TNBC) is usually an aggressive disease with a poor prognosis and limited treatment options. The neurotrophic tyrosine receptor kinase (NTRK) gene fusions are cancer type‐agnostic emerging biomarkers approved by the Food and Drug Administration (FDA), USA, for...

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Detalhes bibliográficos

Principais autores:	Federica Zito Marino, Simona Buono, Marco Montella, Rosa Giannatiempo, Francesco Messina, Giovanni Casaretta, Grazia Arpino, Giulia Vita, Francesco Fiorentino, Luigi Insabato, Alessandro Sgambato, Michele Orditura, Renato Franco, Marina Accardo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2023-09-01
coleção:	The Journal of Pathology: Clinical Research
Assuntos:	triple‐negative breast carcinoma neurotrophic tyrosine receptor kinase (NTRK) NTRK fusions NTRK amplification IHC FISH
Acesso em linha:	https://doi.org/10.1002/cjp2.324
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