The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia

Neuroinflammation is a unifying factor among all acute central nervous system (CNS) injuries and chronic neurodegenerative disorders. Here, we used immortalized microglial (IMG) cells and primary microglia (PMg) to understand the roles of the GTPase Ras homolog gene family member A (RhoA) and its do...

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Hlavní autoři:	Elliot J. Glotfelty, Luis B. Tovar-y-Romo, Shih-Chang Hsueh, David Tweedie, Yazhou Li, Brandon K. Harvey, Barry J. Hoffer, Tobias E. Karlsson, Lars Olson, Nigel H. Greig
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-05-01
Edice:	Cells
Témata:	ROCK1 ROCK2 RhoA microglia neuroinflammation ROCK inhibitors
On-line přístup:	https://www.mdpi.com/2073-4409/12/10/1367
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