RhoA/Rock activation represents a new mechanism for inactivating Wnt/β-catenin signaling in the aging-associated bone loss

Abstract The Wnt/β-catenin signaling pathway appears to be particularly important for bone homeostasis, whereas nuclear accumulation of β-catenin requires the activation of Rac1, a member of the Rho small GTPase family. The aim of the present study was to investigate the role of RhoA/Rho kinase (Roc...

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Detaylı Bibliyografya

Asıl Yazarlar:	Wei Shi, Chengyun Xu, Ying Gong, Jirong Wang, Qianlei Ren, Ziyi Yan, Liu Mei, Chao Tang, Xing Ji, Xinhua Hu, Meiyu Qv, Musaddique Hussain, Ling-Hui Zeng, Ximei Wu
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	SpringerOpen 2021-03-01
Seri Bilgileri:	Cell Regeneration
Konular:	RhoA Rock Wnt β-Catenin Limb bud Bone
Online Erişim:	https://doi.org/10.1186/s13619-020-00071-3
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