Recipient‐derived macrophages mediate acute cardiac allograft rejection via GSDMD‐induced pyroptosis mechanism
Abstract Objective To determine whether macrophage gasdermin D (GSDMD)‐dependent pyroptosis drives acute cardiac allograft rejection and whether targeting GSDMD improves graft survival. Methods GSDMD activation was assessed by immunoblotting. Graft survival wasanalysed in global and macrophage‐speci...
Salvato in:
| Autori principali: | , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley
2026-07-01
|
| Serie: | Clinical and Translational Medicine |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1002/ctm2.70729 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|