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Hepatitis C Virus Down-Regulates the Expression of Ribonucleotide Reductases to Promote Its Replication

Ribonucleotide reductases (RRs or RNRs) catalyze the reduction of the OH group on the 2nd carbon of ribose, reducing four ribonucleotides (NTPs) to the corresponding deoxyribonucleotides (dNTPs) to promote DNA synthesis. Large DNA viruses, such as herpesviruses and poxviruses, could benefit their re...

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Auteurs principaux: Chee-Hing Yang, Cheng-Hao Wu, Shih-Yen Lo, Ahai-Chang Lua, Yu-Ru Chan, Hui-Chun Li
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2023-06-01
Collection:Pathogens
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Accès en ligne:https://www.mdpi.com/2076-0817/12/7/892
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