Clinical mutational profiling and categorization of BRAF mutations in melanomas using next generation sequencing
Abstract Background Analysis of melanomas for actionable mutations has become the standard of care. Recently, a classification scheme has been proposed that categorizes BRAF mutations based on their mechanisms for activation of the MAPK pathway. Methods In this analysis BRAF, KIT, NRAS, and PIK3CA m...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2019-07-01
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| coleção: | BMC Cancer |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12885-019-5864-1 |
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