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Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin

The interactions of novel anti-cancer therapeutic agents with the different plasma and tissue components, specifically serum albumins, have lately gained considerable attention due to the significant influence of such interactions on the pharmacokinetics and/or -dynamics of this important class of t...

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Autores principales: Abdulrahman A. Almehizia, Haitham AlRabiah, Ahmed H. Bakheit, Eman S. G. Hassan, Rashed N. Herqash, Ali Saber Abdelhameed
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2020-01-01
Colección:Royal Society Open Science
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Acceso en línea:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191595
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