Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach

Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA). Neratinib blocks HER2 signaling and is effective in trastu...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Tanveer A. Wani, Ahmed H. Bakheit, M. A. Abounassif, Seema Zargar
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-03-01
Edice:	Frontiers in Chemistry
Témata:	bovine serum albumin neratinib human serum albumin fluorescence quenching
On-line přístup:	http://journal.frontiersin.org/article/10.3389/fchem.2018.00047/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!