Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2
Abstract Angiopoietin‐1 (Ang1) activation of Tie2 receptors on endothelial cells (ECs) reduces adhesion by tumor cells (TCs) and limits junctional permeability to TC diapedesis. We hypothesized that systemic therapy with Vasculotide (VT)—a purported Ang1 mimetic, Tie2 agonist—can reduce the extravas...
保存先:
| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Nature
2015-04-01
|
| シリーズ: | EMBO Molecular Medicine |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.15252/emmm.201404193 |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|