Overexpression of alpha-synuclein promotes both cell proliferation and cell toxicity in human SH-SY5Y neuroblastoma cells

Alpha-Synuclein (aSyn) is a chameleon-like protein. Its overexpression and intracellular deposition defines neurodegenerative α-synucleinopathies including Parkinson’s disease. Whether aSyn up-regulation is the cause or the protective reaction to α-synucleinopathies remains unresolved. Remarkably, t...

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Autors principals:	Noela Rodríguez-Losada, Javier de la Rosa, María Larriva, Rune Wendelbo, José A. Aguirre, Javier S. Castresana, Santiago J. Ballaz
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2020-05-01
Col·lecció:	Journal of Advanced Research
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2090123220300096
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