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Reproducibility of the Infinium methylationEPIC BeadChip assay using low DNA amounts

The Infinium MethylationEPIC BeadChip (EPIC) is a reliable method for measuring the DNA methylation of more than 850,000 CpG positions. In clinical and forensic settings, it is critical to be able to work with low DNA amounts without risking reduced reproducibility. We evaluated the EPIC for a range...

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Main Authors: Steffan Noe Christiansen, Jeppe Dyrberg Andersen, Marie-Louise Kampmann, Jing Liu, Mikkel Meyer Andersen, Jacob Tfelt-Hansen, Niels Morling
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2022-12-01
Series:Epigenetics
Subjects:
dna methylation
illumina methylationepic array
variability
correlation
reproducibility
low dna amounts
Online Access:http://dx.doi.org/10.1080/15592294.2022.2051861
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