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Reproducibility of the Infinium methylationEPIC BeadChip assay using low DNA amounts

The Infinium MethylationEPIC BeadChip (EPIC) is a reliable method for measuring the DNA methylation of more than 850,000 CpG positions. In clinical and forensic settings, it is critical to be able to work with low DNA amounts without risking reduced reproducibility. We evaluated the EPIC for a range...

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Principais autores: Steffan Noe Christiansen, Jeppe Dyrberg Andersen, Marie-Louise Kampmann, Jing Liu, Mikkel Meyer Andersen, Jacob Tfelt-Hansen, Niels Morling
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2022-12-01
coleção:Epigenetics
Assuntos:
dna methylation
illumina methylationepic array
variability
correlation
reproducibility
low dna amounts
Acesso em linha:http://dx.doi.org/10.1080/15592294.2022.2051861
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