Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling

Objective: Exploitation of protective metabolic pathways within injured myocardium still remains an unclarified therapeutic target in heart disease. Moreover, while the roles of altered fatty acid and glucose metabolism in the failing heart have been explored, the influence of highly dynamic and nut...

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Bibliografiske detaljer

Principais autores:	Rebecca C. Schugar, Ashley R. Moll, D. André d’Avignon, Carla J. Weinheimer, Attila Kovacs, Peter A. Crawford
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2014-10-01
Serier:	Molecular Metabolism
Fag:	Myocardial ketone body metabolism Nuclear magnetic resonance (NMR) measurement of substrate metabolism Ventricular remodeling Oxidative stress Mitochondrial metabolism
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2212877814001367
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