VX-765 inhibits pyroptosis and reduces inflammation to prevent acute liver failure by upregulating PPARα expression

Introduction and Objectives: As a fatal clinical syndrome, acute liver failure (ALF) is characterized by overwhelming liver inflammation and hepatic cell death. Finding new therapeutic methods has been a challenge in ALF research. VX-765 is a known pyroptosis inhibitor and has been reported to preve...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Mingjing Jiao, Jiachao Wang, Wenpeng Liu, Xin Zhao, Yanjun Qin, Chunhuan Zhang, Hongzhu Yin, Caiyan Zhao
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2023-05-01
Цуврал:	Annals of Hepatology
Нөхцлүүд:	VX-765 NF-κB Acute liver failure Pyroptosis Peroxisome proliferator-activated receptor α
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S1665268123001862
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!