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VX‐765 alleviates motor and cognitive impairments via inhibiting PANoptosis activation in the neonatal rats after hypoxic–ischemic brain damage

Abstract Neonatal hypoxia–ischemia (HI) is one of the main factors that cause neonatal severe neurologic impairment and death. Shown by a large number of studies, caspase‐1 plays a significant effect in diseases such as hypoxic–ischemic brain damage (HIBD) and may be a key component of the protein c...

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Furkejuvvon:
Váldodahkkit: Xiaohuan Li, Mulan Chen, Boqing Xu, Yepeng Fan, Chunfang Dai, Zhifang Dong
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Wiley 2025-03-01
Ráidu:Pediatric Discovery
Fáttát:
caspase‐1
hypoxic‐ischemic encephalopathy
neuroinflammation
PANoptosis
VX‐765
Liŋkkat:https://doi.org/10.1002/pdi3.66
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