Inhibition of SDE2 promotes autophagy-dependent ferroptosis in multiple myeloma

Background: Multiple myeloma (MM) is an incurable plasma cell malignancy with high relapse rate. Recent studies have implicated dysregulated autophagy and ferroptosis in MM progression; however, the molecular links remain elusive. This study investigated the role of SDE2, a ubiquitin-like protein ov...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Liang Xia, Jing Bao, Xiao-wen Chen, Yu-Chen Zhao, Xiang Wang, Yu Zheng
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2026-04-01
Цуврал:	Redox Biology
Нөхцлүүд:	Multiple myeloma SDE2 ATG5 Autophagy Ferroptosis Ubiquitination
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2213231726000054
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!