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Contrast input and manual interventions significantly affect FreeSurfer morphometry and clinical correlations

FreeSurfer is a widely used software for quantification of brain morphometrics in studies of neurodegeneration and aging. However, choice of input MRI contrast(s) and manual editing are variable across studies and their influence on clinically relevant outcomes remains unclear. Using non-demented, o...

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Hoofdauteurs: Haley E. Wiskoski, Raza Mushtaq, Simeon Smith, Caleb Boehler, Summan Zahra, Juan C. Arias, Scott R. French, Gavin Culwell, Loi Do, Cris Escareno, Emma Heitkamp, Franchell Vazquez, Edward J. Bedrick, Kevin Johnson, Maria Altbach, Gene E. Alexander, Theodore P. Trouard, Craig C. Weinkauf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2026-04-01
Reeks:NeuroImage
Onderwerpen:
FreeSurfer
Surface area
Thickness
Morphometry
Segmentation
Manual edits
Online toegang:http://www.sciencedirect.com/science/article/pii/S1053811926001485
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