Contrast input and manual interventions significantly affect FreeSurfer morphometry and clinical correlations

FreeSurfer is a widely used software for quantification of brain morphometrics in studies of neurodegeneration and aging. However, choice of input MRI contrast(s) and manual editing are variable across studies and their influence on clinically relevant outcomes remains unclear. Using non-demented, o...

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Autori principali:	Haley E. Wiskoski, Raza Mushtaq, Simeon Smith, Caleb Boehler, Summan Zahra, Juan C. Arias, Scott R. French, Gavin Culwell, Loi Do, Cris Escareno, Emma Heitkamp, Franchell Vazquez, Edward J. Bedrick, Kevin Johnson, Maria Altbach, Gene E. Alexander, Theodore P. Trouard, Craig C. Weinkauf
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2026-04-01
Serie:	NeuroImage
Soggetti:	FreeSurfer Surface area Thickness Morphometry Segmentation Manual edits
Accesso online:	http://www.sciencedirect.com/science/article/pii/S1053811926001485
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