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Transcription of a 5’ extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter

Cell differentiation programs require dynamic regulation of gene expression. During meiotic prophase in Saccharomyces cerevisiae, expression of the kinetochore complex subunit Ndc80 is downregulated by a 5’ extended long undecoded NDC80 transcript isoform. Here we demonstrate a transcriptional inter...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Minghao Chia, Amy Tresenrider, Jingxun Chen, Gianpiero Spedale, Victoria Jorgensen, Elçin Ünal, Folkert Jacobus van Werven
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications Ltd 2017-09-01
Cyfres:eLife
Pynciau:
Mynediad Ar-lein:https://elifesciences.org/articles/27420
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!