KLF13 promotes ferroptosis and chemosensitivity in lung adenocarcinoma

Abstract Background Ferroptosis, a form of cell death reliant on iron metabolism dysregulation and lipid peroxidation, has emerged as a promising target for improving tumor drug resistance. This study aims to unveil the underlying molecular mechanisms of Kruppel-like factor 13 (KLF13) in ferroptosis...

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Autors principals:	Haochun Shi, Binyang Pan, Gujie Wu, Jiaqi Liang, Yunyi Bian, Guangyao Shan, Shencheng Ren, Guoshu Bi, Cheng Zhan, Weigang Guo
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-07-01
Col·lecció:	BMC Biology
Matèries:	KLF13 Ferroptosis Chemotherapy GPX4 Lung adenocarcinoma
Accés en línia:	https://doi.org/10.1186/s12915-025-02303-x
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