Deep immune-phenotyping of HLA-homozygous iPS-cardiomyocytes by spectral flow cytometry

IntroductionImmunogenicity of allogeneic human induced pluripotent stem cell (hiPSC)-derived transplants limits their applicability in regenerative medicine. Selecting human leukocyte antigen (HLA)-homozygous hiPSC lines could be a mitigation strategy and haplo-matching would profoundly expand the n...

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Autori principali:	Nicole Maeding, Deepika Suresh Kundully, Anna Steinhuber, Nils Kriedemann, Carlos A. Hernandez-Bautista, Soraia Martins, Sarah Hochmann, Martin Wolf, Wolfgang Mayr, Christof Jungbauer, Sebastian Diecke, Torsten Tonn, Boris Greber, Robert Zweigerdt, Dirk Strunk
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-02-01
Serie:	Frontiers in Immunology
Soggetti:	cardiomyocyte hiPSC immunophenotyping regenerative medicine spectral flow cytometry transplantation immunology
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1736994/full
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