Deep immune-phenotyping of HLA-homozygous iPS-cardiomyocytes by spectral flow cytometry

IntroductionImmunogenicity of allogeneic human induced pluripotent stem cell (hiPSC)-derived transplants limits their applicability in regenerative medicine. Selecting human leukocyte antigen (HLA)-homozygous hiPSC lines could be a mitigation strategy and haplo-matching would profoundly expand the n...

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Hlavní autoři:	Nicole Maeding, Deepika Suresh Kundully, Anna Steinhuber, Nils Kriedemann, Carlos A. Hernandez-Bautista, Soraia Martins, Sarah Hochmann, Martin Wolf, Wolfgang Mayr, Christof Jungbauer, Sebastian Diecke, Torsten Tonn, Boris Greber, Robert Zweigerdt, Dirk Strunk
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-02-01
Edice:	Frontiers in Immunology
Témata:	cardiomyocyte hiPSC immunophenotyping regenerative medicine spectral flow cytometry transplantation immunology
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1736994/full
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