Generation and characterization of a human iPSC line SANi005-A containing the gray platelet associated heterozygous mutation p.Q287* in GFI1B

Peripheral blood mononuclear cells were isolated from an individual harboring a heterozygous c.859C → T p.Q287* mutation in GFI1B, causing an autosomal dominant bleeding disorder, platelet type, 17 (BDPLT17). PBMCs were differentiated to erythroblasts and reprogrammed by lentiviral delivery of a sel...

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Principais autores:	Marten Hansen, Eszter Varga, Tatjana Wüst, Clemens Mellink, Anne-Marie van der Kevie-Kersemaekers, Anne E. Marneth, Marieke von Lindern, Bert van der Reijden, Emile van den Akker
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2017-12-01
Series:	Stem Cell Research
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S1873506117302088
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