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Deletion of the major Escherichia coli multidrug transporter AcrB reveals transporter plasticity and redundancy in bacterial cells.

Multidrug Transporters (MDTs) are major contributors to the acquisition and maintenance of Antimicrobial Resistance (AMR), a growing public health threat of broad concern. Despite the large number of MDTs, the overwhelming majority of the studies performed thus far in Gram-negative bacteria emphasiz...

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Autors principals: Noémie Alon Cudkowicz, Shimon Schuldiner
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2019-01-01
Col·lecció:PLoS ONE
Accés en línia:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0218828/1/pone.0218828.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210222%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210222T205755Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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