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Computational modeling and confirmation of leukemia-associated minor histocompatibility antigens

Abstract: T-cell responses to minor histocompatibility antigens (mHAs) mediate both antitumor immunity (graft-versus-leukemia [GVL]) and graft-versus-host disease (GVHD) in allogeneic stem cell transplant. Identifying mHAs with high allele frequency, tight binding affinity to common HLA molecules, a...

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主要な著者: Jefferson L. Lansford, Udara Dharmasiri, Shengjie Chai, Sally A. Hunsucker, Dante S. Bortone, James E. Keating, Ian M. Schlup, Gary L. Glish, Edward J. Collins, Gheath Alatrash, Jeffrey J. Molldrem, Paul M. Armistead, Benjamin G. Vincent
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2018-08-01
シリーズ:Blood Advances
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S247395292030882X
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