Extracellular vesicles derived from induced pluripotent stem cells mediate anti-inflammatory effects in primary human macrophages

Abstract Extracellular vesicles derived from induced pluripotent stem cells (iPSC EVs) have immunoregulatory potential with the ability to alter the macrophage phenotype. Modulating the macrophage phenotype towards an anti-inflammatory, pro-resolving state may be beneficial in the treatment of chron...

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Hlavní autoři:	Stephen Fitzsimons, Silvia Oggero, Billy P. Egan, Eugène T. Dillon, María Muñoz-San Martín, Shane Clerkin, Ciarán Kennedy, Jessica Davis, Darrell Andrews, John Crean, Orina Belton
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-05-01
Edice:	Scientific Reports
Témata:	Extracellular vesicles iPSCs Macrophages Monocytes Inflammation
On-line přístup:	https://doi.org/10.1038/s41598-026-49621-w
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